![]() ![]() Speak with your doctor before supplementing. In general, regulatory bodies aren’t assuring the quality, safety, and efficacy of supplements. Wound healing: 2% GSE cream, 2x daily for 3 weeks ĭespite the promising clinical and preclinical research, grape seed extract supplements have not been approved by the FDA for medical use.Anti-aging: 2% GSE cream, 2x daily for 2 months.Skin appearance: 200 mg daily for 6 months įor grape seed extract skin application, the following formulations were used:.Kidney disease: 2000 mg daily for 6 months.Mental health and cognition: 250 mg daily for 12 weeks.Blood pressure and heart disease prevention: 300-2000 mg for 4+ weeks.Antioxidant support: 600 mg daily for 5 days.Children and Pregnant WomenĬhildren and pregnant and breastfeeding women should avoid grape seed extract because we still lack evidence of its safety in these sensitive groups. These toxins have not been reported to occur in grape seed extract. On the other hand, juice and red wine from sold in Brazil contained the yeast toxin called Ochratoxin A. For example, pesticides were found in most grape juice products produced and sold in Canada. ![]() Pesticides and yeast toxins have been identified in grape skin, juice, and wine made from grapes in some regions of the world. If you do, you can combine it with vitamin C to improve iron absorption. To avoid iron deficiency, don’t take grape seed extract supplements with iron-rich foods (meat, legumes, greens). Grape seeds and other foods rich in polyphenols may hinder iron absorption. People who are allergic to grapes shouldn’t use grape seed extract.Īnimal safety studies suggested that grape seed extract was safe in long-term lab settings, but proper human safety data are lacking. ![]() The following side effects have been reported : Grape seed extract was safe in clinical trials, mostly causing side effects at rates similar to placebo. Supplement manufacturers usually source grape seeds from winemakers, and they extract proanthocyanidins and other healthy components.įor other grape seed products and their uses, check out the FAQ section below. Grape seed extract is a concentrated source of antioxidant polyphenols from grape seeds. Grape Seed Extract Side Effects & Safety Overview ![]() Learn about the dosage range used in clinical trials, reported side effects, and what users say about different GSE supplements. Many GSE products are available, but their quality and safety can greatly vary. Grape seed extract (GSE) is packed with polyphenols and other antioxidants. A plus sign next to the number “” means that the information is found within the full scientific study rather than the abstract. Note that each number in parentheses is a clickable link to peer-reviewed scientific studies. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at Our goal is to not have a single piece of inaccurate information on this website. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists.Īll of our content is written by scientists and people with a strong science background. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. We believe that the most accurate information is found directly in the scientific source. SelfHacked has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed. ![]()
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